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BMCBI
2008
323views more  BMCBI 2008»
13 years 10 months ago
A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data
Background: Alternative splicing is an important gene regulation mechanism. It is estimated that about 74% of multi-exon human genes have alternative splicing. High throughput tan...
Fan Mo, Xu Hong, Feng Gao, Lin Du, Jun Wang, Gilbe...
BMCBI
2007
127views more  BMCBI 2007»
13 years 10 months ago
The EIPeptiDi tool: enhancing peptide discovery in ICAT-based LC MS/MS experiments
Background: Isotope-coded affinity tags (ICAT) is a method for quantitative proteomics based on differential isotopic labeling, sample digestion and mass spectrometry (MS). The me...
Mario Cannataro, Giovanni Cuda, Marco Gaspari, Ser...
BIB
2011
13 years 4 months ago
Protein mass spectra data analysis for clinical biomarker discovery: a global review
The identification of new diagnostic or prognostic biomarkers is one of the main aims of clinical cancer research. In recent years there has been a growing interest in using high ...
Pascal Roy, Caroline Truntzer, Delphine Maucort-Bo...
BMCBI
2010
117views more  BMCBI 2010»
13 years 10 months ago
Better score function for peptide identification with ETD MS/MS spectra
Background: Tandem mass spectrometry (MS/MS) has become the primary way for protein identification in proteomics. A good score function for measuring the match quality between a p...
Xiaowen Liu, Baozhen Shan, Lei Xin, Bin Ma
IJAR
2008
93views more  IJAR 2008»
13 years 9 months ago
Prototype based fuzzy classification in clinical proteomics
Proteomic profiling based on mass spectrometry is an important tool for studies at the protein and peptide level in medicine and health care. Thereby, the identification of releva...
Frank-Michael Schleif, Thomas Villmann, Barbara Ha...