Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...
Background: Functional genomics involves the parallel experimentation with large sets of proteins. This requires management of large sets of open reading frames as a prerequisite ...
Clustering problems often involve datasets where only a part of the data is relevant to the problem, e.g., in microarray data analysis only a subset of the genes show cohesive exp...
In many classification and data-mining applications the user does not know a priori which distance measure is the most appropriate for the task at hand without examining the produ...