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BMCBI
2007
148views more  BMCBI 2007»
15 years 4 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
KDD
2004
ACM
302views Data Mining» more  KDD 2004»
16 years 4 months ago
Redundancy based feature selection for microarray data
In gene expression microarray data analysis, selecting a small number of discriminative genes from thousands of genes is an important problem for accurate classification of diseas...
Lei Yu, Huan Liu
BMCBI
2010
181views more  BMCBI 2010»
15 years 4 months ago
Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...
Amit Zeisel, Amnon Amir, Wolfgang J. Köstler,...
RECOMB
2002
Springer
16 years 4 months ago
Discovering local structure in gene expression data: the order-preserving submatrix problem
This paper concerns the discovery of patterns in gene expression matrices, in which each element gives the expression level of a given gene in a given experiment. Most existing me...
Amir Ben-Dor, Benny Chor, Richard M. Karp, Zohar Y...
BMCBI
2006
86views more  BMCBI 2006»
15 years 4 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao