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BMCBI
2007
144views more  BMCBI 2007»
13 years 8 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
ROCAI
2004
Springer
14 years 1 months ago
Learning Mixtures of Localized Rules by Maximizing the Area Under the ROC Curve
We introduce a model class for statistical learning which is based on mixtures of propositional rules. In our mixture model, the weight of a rule is not uniform over the entire ins...
Tobias Sing, Niko Beerenwinkel, Thomas Lengauer
BMCBI
2010
108views more  BMCBI 2010»
13 years 8 months ago
An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs
Background: Transcription factors (TFs) control transcription by binding to specific regions of DNA called transcription factor binding sites (TFBSs). The identification of TFBSs ...
Fernando Garcia-Alcalde, Armando Blanco, Adrian J....
CEC
2011
IEEE
12 years 8 months ago
Cost-benefit analysis of using heuristics in ACGP
—Constrained Genetic Programming (CGP) is a method of searching the Genetic Programming search space non-uniformly, giving preferences to certain subspaces according to some heur...
John W. Aleshunas, Cezary Z. Janikow
COMPUTER
2007
153views more  COMPUTER 2007»
13 years 8 months ago
The Discipline of Embedded Systems Design
ems, using abstractions that actually remove physical constraints from consideration. At the other, embedded systems design goes beyond the traditional expertise of electrical engi...
Thomas A. Henzinger, Joseph Sifakis