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» NITPICK: peak identification for mass spectrometry data
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BMCBI
2006
124views more  BMCBI 2006»
13 years 8 months ago
HybGFS: a hybrid method for genome-fingerprint scanning
Background: Protein identification based on mass spectrometry (MS) has previously been performed using peptide mass fingerprinting (PMF) or tandem MS (MS/MS) database searching. H...
Kosaku Shinoda, Nozomu Yachie, Takeshi Masuda, Nao...
BMCBI
2007
135views more  BMCBI 2007»
13 years 8 months ago
LIMPIC: a computational method for the separation of protein MALDI-TOF-MS signals from noise
Background: Mass spectrometry protein profiling is a promising tool for biomarker discovery in clinical proteomics. However, the development of a reliable approach for the separat...
Dante Mantini, Francesca Petrucci, Damiana Pierago...
BMCBI
2010
124views more  BMCBI 2010»
13 years 8 months ago
A Dynamic Noise Level Algorithm for Spectral Screening of Peptide MS/MS Spectra
Background: High-throughput shotgun proteomics data contain a significant number of spectra from non-peptide ions or spectra of too poor quality to obtain highly confident peptide...
Hua Xu, Michael A. Freitas
BMCBI
2006
153views more  BMCBI 2006»
13 years 8 months ago
2DDB - a bioinformatics solution for analysis of quantitative proteomics data
Background: We present 2DDB, a bioinformatics solution for storage, integration and analysis of quantitative proteomics data. As the data complexity and the rate with which it is ...
Lars Malmström, György Marko-Varga, Guni...
BMCBI
2010
86views more  BMCBI 2010»
13 years 8 months ago
ICC-CLASS: isotopically-coded cleavable crosslinking analysis software suite
Background: Successful application of crosslinking combined with mass spectrometry for studying proteins and protein complexes requires specifically-designed crosslinking reagents...
Evgeniy V. Petrotchenko, Christoph H. Borchers