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» NITPICK: peak identification for mass spectrometry data
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BMCBI
2007
166views more  BMCBI 2007»
13 years 8 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
BMCBI
2010
122views more  BMCBI 2010»
13 years 8 months ago
Ovarian cancer classification based on dimensionality reduction for SELDI-TOF data
Background: Recent advances in proteomics technologies such as SELDI-TOF mass spectrometry has shown promise in the detection of early stage cancers. However, dimensionality reduc...
Kai-Lin Tang, Tong-Hua Li, Wen-Wei Xiong, Kai Chen
NAR
2006
64views more  NAR 2006»
13 years 8 months ago
The PeptideAtlas project
The completion of the sequencing of the human genome and the concurrent, rapid development of high-throughput proteomic methods have resulted in an increasing need for automated a...
Frank Desiere, Eric W. Deutsch, Nichole L. King, A...
BMCBI
2007
99views more  BMCBI 2007»
13 years 8 months ago
The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data
Background: The combination of mass spectrometry and solution phase amide hydrogen/deuterium exchange (H/D exchange) experiments is an effective method for characterizing protein ...
B. D. Pascal, M. J. Chalmers, S. A. Busby, C. C. M...
BMCBI
2007
157views more  BMCBI 2007»
13 years 8 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...