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BMCBI
2010
13 years 11 months ago
2010
Background: Principal component analysis (PCA) has gained popularity as a method for the analysis of highdimensional genomic data. However, it is often difficult to interpret the ...
BMCBI
2010
13 years 11 months ago
2010
Background: The estimation of demographic parameters from genetic data often requires the computation of likelihoods. However, the likelihood function is computationally intractab...
BMCBI
2010
13 years 11 months ago
2010
Background: Recent studies have shown that copy number variations (CNVs) are frequent in higher eukaryotes and associated with a substantial portion of inherited and acquired risk...
BMCBI
2010
13 years 11 months ago
2010
Background: Machine learning techniques have shown to improve bacterial species classification based on fatty acid methyl ester (FAME) data. Nonetheless, FAME analysis has a limit...
BMCBI
2007
13 years 11 months ago
2007
Background: Three-color microarray experiments can be performed to assess drug effects on the genomic scale. The methodology may be useful in shortening the cycle, reducing the co...