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BMCBI
2010
106views more  BMCBI 2010»
13 years 7 months ago
A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
Guofeng Meng, Axel Mosig, Martin Vingron
BMCBI
2010
153views more  BMCBI 2010»
13 years 7 months ago
GOAL: A software tool for assessing biological significance of genes groups
Background: Modern high throughput experimental techniques such as DNA microarrays often result in large lists of genes. Computational biology tools such as clustering are then us...
Alain B. Tchagang, Alexander Gawronski, Hugo B&eac...
BMCBI
2010
129views more  BMCBI 2010»
13 years 7 months ago
A temporal precedence based clustering method for gene expression microarray data
Background: Time-course microarray experiments can produce useful data which can help in understanding the underlying dynamics of the system. Clustering is an important stage in m...
Ritesh Krishna, Chang-Tsun Li, Vicky Buchanan-Woll...
BMCBI
2010
144views more  BMCBI 2010»
13 years 7 months ago
Finding sRNA generative locales from high-throughput sequencing data with NiBLS
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...
Daniel MacLean, Vincent Moulton, David J. Studholm...
BMCBI
2010
175views more  BMCBI 2010»
13 years 7 months ago
The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services
Background: Many complementary solutions are available for the identifier mapping problem. This creates an opportunity for bioinformatics tool developers. Tools can be made to fle...
Martijn P. van Iersel, Alexander R. Pico, Thomas K...
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