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BMCBI
2010
138views more  BMCBI 2010»
13 years 9 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi
BMCBI
2007
168views more  BMCBI 2007»
13 years 9 months ago
Bayesian model-based inference of transcription factor activity
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Simon Rogers, Raya Khanin, Mark Girolami
BMCBI
2007
97views more  BMCBI 2007»
13 years 9 months ago
In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
Tineke Casneuf, Yves Van de Peer, Wolfgang Huber
KDD
2007
ACM
168views Data Mining» more  KDD 2007»
14 years 10 months ago
Finding tribes: identifying close-knit individuals from employment patterns
We present a family of algorithms to uncover tribes--groups of individuals who share unusual sequences of affiliations. While much work inferring community structure describes lar...
Lisa Friedland, David Jensen
AINA
2009
IEEE
14 years 4 months ago
Towards a Rational Approach for the Logical Modelling of Inhibition in Metabolic Networks
—This paper makes two contributions towards the logical modelling of inhibition in metabolic networks. First it exposes the logical inconsistency of an existing state-of-the-art ...
Oliver Ray