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ESWA
2007
100views more  ESWA 2007»
13 years 8 months ago
Using memetic algorithms with guided local search to solve assembly sequence planning
The goal of assembly planning consists in generating feasible sequences to assemble a product and selecting an efficient assembly sequence from which related constraint factors su...
Hwai-En Tseng, Wen-Pai Wang, Hsun-Yi Shih
BMCBI
2010
148views more  BMCBI 2010»
13 years 9 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...
BMCBI
2007
265views more  BMCBI 2007»
13 years 9 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
BMCBI
2008
111views more  BMCBI 2008»
13 years 9 months ago
Probabilistic base calling of Solexa sequencing data
Background: Solexa/Illumina short-read ultra-high throughput DNA sequencing technology produces millions of short tags (up to 36 bases) by parallel sequencing-by-synthesis of DNA ...
Jacques Rougemont, Arnaud Amzallag, Christian Isel...
BMCBI
2006
159views more  BMCBI 2006»
13 years 9 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...