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BMCBI
2010
156views more  BMCBI 2010»
13 years 10 months ago
Estimating the individualized HIV-1 genetic barrier to resistance using a nelfinavir fitness landscape
Background: Failure on Highly Active Anti-Retroviral Treatment is often accompanied with development of antiviral resistance to one or more drugs included in the treatment. In gen...
Kristof Theys, Koen Deforche, Gertjan Beheydt, Yve...
BMCBI
2007
131views more  BMCBI 2007»
13 years 10 months ago
FUNC: a package for detecting significant associations between gene sets and ontological annotations
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
Kay Prüfer, Bjoern Muetzel, Hong Hai Do, Gunt...
BMCBI
2010
178views more  BMCBI 2010»
13 years 10 months ago
Applications of a formal approach to decipher discrete genetic networks
Background: A growing demand for tools to assist the building and analysis of biological networks exists in systems biology. We argue that the use of a formal approach is relevant...
Fabien Corblin, Eric Fanchon, Laurent Trilling
BMCBI
2007
154views more  BMCBI 2007»
13 years 10 months ago
Classification of heterogeneous microarray data by maximum entropy kernel
Background: There is a large amount of microarray data accumulating in public databases, providing various data waiting to be analyzed jointly. Powerful kernel-based methods are c...
Wataru Fujibuchi, Tsuyoshi Kato
BMCBI
2010
201views more  BMCBI 2010»
13 years 10 months ago
Analysis of X-ray Structures of Matrix Metalloproteinases via Chaotic Map Clustering
Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
Ilenia Giangreco, Orazio Nicolotti, Angelo Carotti...
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