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BMCBI
2010
103views more  BMCBI 2010»
13 years 8 months ago
A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...
Alexander G. Churbanov, Igor Vorechovsky, Chindo H...
BMCBI
2008
133views more  BMCBI 2008»
13 years 8 months ago
LocateP: Genome-scale subcellular-location predictor for bacterial proteins
Background: In the past decades, various protein subcellular-location (SCL) predictors have been developed. Most of these predictors, like TMHMM 2.0, SignalP 3.0, PrediSi and Phob...
Miaomiao Zhou, Jos Boekhorst, Christof Francke, Ro...
BMCBI
2007
152views more  BMCBI 2007»
13 years 8 months ago
Bioinformatic identification of novel putative photoreceptor specific cis-elements
Background: Cell specific gene expression is largely regulated by different combinations of transcription factors that bind cis-elements in the upstream promoter sequence. However...
Charles G. Danko, Vera A. McIlvain, Maochun Qin, B...
BMCBI
2006
374views more  BMCBI 2006»
13 years 8 months ago
AMDA: an R package for the automated microarray data analysis
Background: Microarrays are routinely used to assess mRNA transcript levels on a genome-wide scale. Large amount of microarray datasets are now available in several databases, and...
Mattia Pelizzola, Norman Pavelka, Maria Foti, Paol...
BMCBI
2004
143views more  BMCBI 2004»
13 years 8 months ago
Comparing functional annotation analyses with Catmap
Background: Ranked gene lists from microarray experiments are usually analysed by assigning significance to predefined gene categories, e.g., based on functional annotations. Tool...
Thomas Breslin, Patrik Edén, Morten Krogh