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» New journal: Algorithms for Molecular Biology
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BMCBI
2007
157views more  BMCBI 2007»
13 years 7 months ago
A hybrid multiscale Monte Carlo algorithm (HyMSMC) to cope with disparity in time scales and species populations in intracellula
Background: The fundamental role that intrinsic stochasticity plays in cellular functions has been shown via numerous computational and experimental studies. In the face of such e...
Asawari Samant, Babatunde A. Ogunnaike, Dionisios ...
EDBT
2012
ACM
257views Database» more  EDBT 2012»
11 years 10 months ago
Indexing and mining topological patterns for drug discovery
Increased availability of large repositories of chemical compounds has created new challenges and opportunities for the application of data-mining and indexing techniques to probl...
Sayan Ranu, Ambuj K. Singh
BMCBI
2007
216views more  BMCBI 2007»
13 years 7 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
SPIRE
1999
Springer
13 years 11 months ago
Cross-Domain Approximate String Matching
Approximate string matching is an important paradigm in domains ranging from speech recognition to information retrieval and molecular biology. In this paper, we introduce a new f...
Daniel P. Lopresti, Gordon T. Wilfong
BIOCOMP
2006
13 years 9 months ago
PAC: Progressive Alignment with Consensus Sequences
Computation of multiple sequence alignments is one of the major open problems in computational molecular biology. The purpose of this study was to provide a new method, PAC (Progre...
Ke Liu, Mansur H. Samadzadeh