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BIOCOMP
2006
13 years 10 months ago
PAC: Progressive Alignment with Consensus Sequences
Computation of multiple sequence alignments is one of the major open problems in computational molecular biology. The purpose of this study was to provide a new method, PAC (Progre...
Ke Liu, Mansur H. Samadzadeh
BMCBI
2007
154views more  BMCBI 2007»
13 years 9 months ago
Inferring biological networks with output kernel trees
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
BMCBI
2007
136views more  BMCBI 2007»
13 years 9 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
ALGORITHMICA
2002
120views more  ALGORITHMICA 2002»
13 years 9 months ago
An Experimental Study of Algorithms for Weighted Completion Time Scheduling
We consider the total weighted completion time scheduling problem for parallel identical machines and precedence constraints, P jprecj PwiCi. This important and broad class of pro...
Ivan D. Baev, Waleed Meleis, Alexandre E. Eichenbe...
FOCS
2003
IEEE
14 years 2 months ago
Approximation Algorithms for Orienteering and Discounted-Reward TSP
In this paper, we give the rst constant-factor approximationalgorithmfor the rooted Orienteering problem, as well as a new problem that we call the Discounted-Reward TSP, motivate...
Avrim Blum, Shuchi Chawla, David R. Karger, Terran...