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BMCBI
2008
121views more  BMCBI 2008»
13 years 7 months ago
OntoDas - a tool for facilitating the construction of complex queries to the Gene Ontology
Background: Ontologies such as the Gene Ontology can enable the construction of complex queries over biological information in a conceptual way, however existing systems to do thi...
Kieran O'Neill, Alexander García Castro, An...
BMCBI
2007
128views more  BMCBI 2007»
13 years 7 months ago
Model order selection for bio-molecular data clustering
Background: Cluster analysis has been widely applied for investigating structure in bio-molecular data. A drawback of most clustering algorithms is that they cannot automatically ...
Alberto Bertoni, Giorgio Valentini
BMCBI
2010
115views more  BMCBI 2010»
13 years 7 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2004
134views more  BMCBI 2004»
13 years 7 months ago
Bayesian model accounting for within-class biological variability in Serial Analysis of Gene Expression (SAGE)
Background: An important challenge for transcript counting methods such as Serial Analysis of Gene Expression (SAGE), "Digital Northern" or Massively Parallel Signature ...
Ricardo Z. N. Vêncio, Helena Brentani, Diogo...
BMCBI
2006
101views more  BMCBI 2006»
13 years 7 months ago
SynTReN: a generator of synthetic gene expression data for design and analysis of structure learning algorithms
Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
Tim Van den Bulcke, Koen Van Leemput, Bart Naudts,...