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ISAMI
2010
13 years 6 months ago
A Data Mining Approach for the Detection of High-Risk Breast Cancer Groups
It is widely agreed that complex diseases are typically caused by the joint effects of multiple instead of a single genetic variation. These genetic variations may show very little...
Orlando Anunciação, Bruno C. Gomes, ...
NIPS
2007
13 years 10 months ago
Bayesian Inference for Spiking Neuron Models with a Sparsity Prior
Generalized linear models are the most commonly used tools to describe the stimulus selectivity of sensory neurons. Here we present a Bayesian treatment of such models. Using the ...
Sebastian Gerwinn, Jakob Macke, Matthias Seeger, M...
BMCBI
2008
108views more  BMCBI 2008»
13 years 8 months ago
An analysis of the positional distribution of DNA motifs in promoter regions and its biological relevance
Background: Motif finding algorithms have developed in their ability to use computationally efficient methods to detect patterns in biological sequences. However the posterior cla...
Ana C. Casimiro, Susana Vinga, Ana T. Freitas, Arl...
BMCBI
2007
217views more  BMCBI 2007»
13 years 8 months ago
On consensus biomarker selection
Background: Recent development of mass spectrometry technology enabled the analysis of complex peptide mixtures. A lot of effort is currently devoted to the identification of biom...
Janusz Dutkowski, Anna Gambin
RECOMB
2008
Springer
14 years 8 months ago
Accurate Computation of Likelihoods in the Coalescent with Recombination Via Parsimony
Understanding the variation of recombination rates across a given genome is crucial for disease gene mapping and for detecting signatures of selection, to name just a couple of app...
Jotun Hein, Rune B. Lyngsø, Yun S. Song