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BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
Visualizing and clustering high throughput sub-cellular localization imaging
Background: The expansion of automatic imaging technologies has created a need to be able to efficiently compare and review large sets of image data. To enable comparisons of imag...
Nicholas A. Hamilton, Rohan D. Teasdale
BMCBI
2008
115views more  BMCBI 2008»
13 years 7 months ago
Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson corre...
Jianchao Yao, Chunqi Chang, Mari L. Salmi, Yeung S...
BMCBI
2007
148views more  BMCBI 2007»
13 years 7 months ago
BPhyOG: An interactive server for genome-wide inference of bacterial phylogenies based on overlapping genes
Background: Overlapping genes (OGs) in bacterial genomes are pairs of adjacent genes of which the coding sequences overlap partly or entirely. With the rapid accumulation of seque...
Yingqin Luo, Cong Fu, Da-Yong Zhang, Kui Lin
BMCBI
2007
181views more  BMCBI 2007»
13 years 7 months ago
Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases
Background: In recent years, mammalian protein-protein interaction network databases have been developed. The interactions in these databases are either extracted manually from lo...
Seth I. Berger, Jeremy M. Posner, Avi Ma'ayan
BMCBI
2007
146views more  BMCBI 2007»
13 years 7 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...