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BMCBI
2007
163views more  BMCBI 2007»
13 years 8 months ago
Strainer: software for analysis of population variation in community genomic datasets
Background: Metagenomic analyses of microbial communities that are comprehensive enough to provide multiple samples of most loci in the genomes of the dominant organism types will...
John M. Eppley, Gene W. Tyson, Wayne M. Getz, Jill...
BMCBI
2008
94views more  BMCBI 2008»
13 years 8 months ago
Structural assembly of two-domain proteins by rigid-body docking
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
Tammy M. K. Cheng, Tom L. Blundell, Juan Fern&aacu...
BMCBI
2006
103views more  BMCBI 2006»
13 years 8 months ago
Correction of scaling mismatches in oligonucleotide microarray data
Background: Gene expression microarray data is notoriously subject to high signal variability. Moreover, unavoidable variation in the concentration of transcripts applied to micro...
Martino Barenco, Jaroslav Stark, Daniel Brewer, Da...
BMCBI
2006
118views more  BMCBI 2006»
13 years 8 months ago
Exploration of biological network centralities with CentiBiN
Background: The elucidation of whole-cell regulatory, metabolic, interaction and other biological networks generates the need for a meaningful ranking of network elements. Central...
Björn H. Junker, Dirk Koschützki, Falk S...
BMCBI
2006
172views more  BMCBI 2006»
13 years 8 months ago
A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
Background: Tandem mass spectrometry (MS/MS) is a powerful tool for protein identification. Although great efforts have been made in scoring the correlation between tandem mass sp...
Zhuo Zhang, Shiwei Sun, Xiaopeng Zhu, Suhua Chang,...