Background: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the la...
Tao Han, Jianyong Wang, Weida Tong, Martha M. Moor...
Background: Identification of biomarkers among thousands of genes arrayed for disease classification has been the subject of considerable research in recent years. These studies h...
Liping Huang, Wenying Zhu, Christopher P. Saunders...
Motivation: The need for normalization in microarray experiments has been well documented in the literature. Currently, most analysis methods treat normalization and analysis as a...
Ann L. Oberg, Douglas W. Mahoney, Karla V. Ballman...
Background: It is an important pre-processing step to accurately estimate missing values in microarray data, because complete datasets are required in numerous expression profile ...
Background: Regulation of gene expression is relevant to many areas of biology and medicine, in the study of treatments, diseases, and developmental stages. Microarrays can be use...