Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
Abstract-- The RNA secondary structure design (SSD) problem is a recently emerging research topic motivated by applications such as customized drug design and the self-assembly of ...
Standard hidden Markov models (HMM's) have been studied extensively in the last two decades. It is well known that these models assume state conditional independence of the ob...
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
We present a novel approach for structure prediction that addresses the difficulty of obtaining labeled structures for training. We observe that structured output problems often h...
Ming-Wei Chang, Vivek Srikumar, Dan Goldwasser, Da...