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» Numerical simulation of stochastic gene circuits
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CCE
2005
13 years 10 months ago
Numerical simulation of stochastic gene circuits
Armed with increasingly fast supercomputers and greater knowledge of the molecular mechanisms of gene expression, it is now practical to numerically simulate complex networks of r...
Howard Salis, Yiannis N. Kaznessis
BMCBI
2004
323views more  BMCBI 2004»
13 years 10 months ago
Biochemical Network Stochastic Simulator (BioNetS): software for stochastic modeling of biochemical networks
Background: Intrinsic fluctuations due to the stochastic nature of biochemical reactions can have large effects on the response of biochemical networks. This is particularly true ...
David Adalsteinsson, David McMillen, Timothy C. El...
ICCAD
2001
IEEE
217views Hardware» more  ICCAD 2001»
14 years 7 months ago
ASF: A Practical Simulation-Based Methodology for the Synthesis of Custom Analog Circuits
: This paper describes ASF, a novel cell-level analog synthesis framework that can size and bias a given circuit topology subject to a set of performance objectives and a manufactu...
Michael Krasnicki, Rodney Phelps, James R. Hellums...
CMSB
2006
Springer
14 years 2 months ago
Regulatory Network Reconstruction Using Stochastic Logical Networks
Abstract. This paper presents a method for regulatory network reconstruction from experimental data. We propose a mathematical model for regulatory interactions, based on the work ...
Bartek Wilczynski, Jerzy Tiuryn
HYBRID
2001
Springer
14 years 3 months ago
Hybrid Modeling and Simulation of Biomolecular Networks
Abstract. In a biological cell, cellular functions and the genetic regulatory apparatus are implemented and controlled by a network of chemical reactions in which regulatory protei...
Rajeev Alur, Calin Belta, Franjo Ivancic