— This work presents a methodology for the application of a parallel genetic algorithm (PGA) to the problem of protein folding prediction, using the 3DHP-Side Chain model. This m...
Many non-coding RNA genes and cis-acting regulatory elements of mRNAs contain RNA secondary structures that are critical for their function. Such functional RNAs can be predicted ...
nt programs require high-level abstractions in order to manage complexity and enable compositional reasoning. In this paper, we introduce a novel concurrency abstraction, dubbed t...
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Prediction and alignment of RNA pseudoknot structures are NP-hard. Nevertheless, several efficient prediction algorithms by dynamic programming have been proposed for restricted cl...