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» On Compressibility of Protein Sequences
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BMCBI
2010
123views more  BMCBI 2010»
13 years 10 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
BMCBI
2006
112views more  BMCBI 2006»
13 years 10 months ago
Algorithms for incorporating prior topological information in HMMs: application to transmembrane proteins
Background: Hidden Markov Models (HMMs) have been extensively used in computational molecular biology, for modelling protein and nucleic acid sequences. In many applications, such...
Pantelis G. Bagos, Theodore D. Liakopoulos, Stavro...
BMCBI
2005
142views more  BMCBI 2005»
13 years 10 months ago
High performance workflow implementation for protein surface characterization using grid technology
Background: This study concerns the development of a high performance workflow that, using grid technology, correlates different kinds of Bioinformatics data, starting from the ba...
Ivan Merelli, Giulia Morra, Daniele D'Agostino, An...
BMCBI
2010
121views more  BMCBI 2010»
13 years 10 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
BMCBI
2008
128views more  BMCBI 2008»
13 years 10 months ago
An efficient visualization tool for the analysis of protein mutation matrices
Background: It is useful to develop a tool that would effectively describe protein mutation matrices specifically geared towards the identification of mutations that produce eithe...
Maria Pamela C. David, Carlo M. Lapid, Vincent Ric...