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» On Compressibility of Protein Sequences
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BMCBI
2004
88views more  BMCBI 2004»
13 years 8 months ago
Coronavirus 3CLpro proteinase cleavage sites: Possible relevance to SARS virus pathology
Background: Despite the passing of more than a year since the first outbreak of Severe Acute Respiratory Syndrome (SARS), efficient counter-measures are still few and many believe...
Lars Kiemer, Ole Lund, Søren Brunak, Nikola...
NAR
2011
208views Computer Vision» more  NAR 2011»
12 years 11 months ago
MIPS: curated databases and comprehensive secondary data resources in 2010
The Munich Information Center for Protein Sequences (MIPS at the Helmholtz Center for Environmental Health, Neuherberg, Germany) has many years of experience in providing annotate...
Hans-Werner Mewes, Andreas Ruepp, Fabian J. Theis,...
LION
2009
Springer
114views Optimization» more  LION 2009»
14 years 3 months ago
Substitution Matrices and Mutual Information Approaches to Modeling Evolution
Abstract. Substitution matrices are at the heart of Bioinformatics: sequence alignment, database search, phylogenetic inference, protein family classication are based on Blosum, P...
Stephan Kitchovitch, Yuedong Song, Richard C. van ...
CSB
2003
IEEE
108views Bioinformatics» more  CSB 2003»
14 years 2 months ago
A Pattern Matching Algorithm for Codon Optimization and CpG Motif-Engineering in DNA Expression Vectors
Codon optimization enhances the efficiency of DNA expression vectors used in DNA vaccination and gene therapy by increasing protein expression. Additionally, certain nucleotide mo...
Ravi Vijaya Satya, Amar Mukherjee, Udaykumar Ranga
CORR
2010
Springer
157views Education» more  CORR 2010»
13 years 9 months ago
Efficient Clustering with Limited Distance Information
Given a point set S and an unknown metric d on S, we study the problem of efficiently partitioning S into k clusters while querying few distances between the points. In our model ...
Konstantin Voevodski, Maria-Florina Balcan, Heiko ...