Assigning functions to novel proteins is one of the most important problems in the post-genomic era. Several approaches have been applied to this problem, including analyzing gene...
Minghua Deng, Kui Zhang, Shipra Mehta, Ting Chen, ...
Background: Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, un...
Chilamakuri C. S. Reddy, Khader Shameer, Bernard O...
Background: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human prote...
Simon K. Chan, Michael Hsing, Fereydoun Hormozdiar...
Compression based pattern mining has been successfully applied to many data mining tasks. We propose an approach based on the minimum description length principle to extract seque...
Background: Annotation of sequences that share little similarity to sequences of known function remains a major obstacle in genome annotation. Some of the best methods of detectin...