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» On Compressibility of Protein Sequences
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BMCBI
2006
120views more  BMCBI 2006»
13 years 9 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu
BMCBI
2006
149views more  BMCBI 2006»
13 years 9 months ago
Curation of viral genomes: challenges, applications and the way forward
Background: Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing ...
Urmila Kulkarni-Kale, Shriram Bhosle, G. Sunitha M...
BMCBI
2007
137views more  BMCBI 2007»
13 years 8 months ago
PlnTFDB: an integrative plant transcription factor database
Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...
Diego Mauricio Riaño-Pachón, Sloboda...
JCB
2006
138views more  JCB 2006»
13 years 8 months ago
Recognition and Classification of Histones Using Support Vector Machine
Histones are DNA-binding proteins found in the chromatin of all eukaryotic cells. They are highly conserved and can be grouped into five major classes: H1/H5, H2A, H2B, H3, and H4...
Manoj Bhasin, Ellis L. Reinherz, Pedro A. Reche
NAR
2006
83views more  NAR 2006»
13 years 8 months ago
KOBAS server: a web-based platform for automated annotation and pathway identification
There is an increasing need to automatically annotate a set of genes or proteins (from genome sequencing, DNA microarray analysis or protein 2D gel experiments) using controlled v...
Jianmin Wu, Xizeng Mao, Tao Cai, Jingchu Luo, Lipi...