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» On Compressibility of Protein Sequences
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BMCBI
2007
121views more  BMCBI 2007»
13 years 8 months ago
A procedure for identifying homologous alternative splicing events
Background: The study of the functional role of alternative splice isoforms of a gene is a very active area of research in biology. The difficulty of the experimental approach (in...
David Talavera, Adam Hospital, Modesto Orozco, Xav...
BMCBI
2008
82views more  BMCBI 2008»
13 years 8 months ago
Studying the functional conservation of cis-regulatory modules and their transcriptional output
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...
Denis C. Bauer, Timothy L. Bailey
BMCBI
2007
108views more  BMCBI 2007»
13 years 8 months ago
Publishing perishing? Towards tomorrow's information architecture
Scientific articles are tailored to present information in human-readable aliquots. Although the Internet has revolutionized the way our society thinks about information, the trad...
Michael R. Seringhaus, Mark B. Gerstein
BMCBI
2008
146views more  BMCBI 2008»
13 years 8 months ago
nGASP - the nematode genome annotation assessment project
Background: While the C. elegans genome is extensively annotated, relatively little information is available for other Caenorhabditis species. The nematode genome annotation asses...
Avril Coghlan, Tristan J. Fiedler, Sheldon J. McKa...
BMCBI
2007
99views more  BMCBI 2007»
13 years 8 months ago
The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data
Background: The combination of mass spectrometry and solution phase amide hydrogen/deuterium exchange (H/D exchange) experiments is an effective method for characterizing protein ...
B. D. Pascal, M. J. Chalmers, S. A. Busby, C. C. M...