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» On Compressibility of Protein Sequences
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BMCBI
2008
87views more  BMCBI 2008»
13 years 10 months ago
Protein structure search and local structure characterization
Background: Structural similarities among proteins can provide valuable insight into their functional mechanisms and relationships. As the number of available three-dimensional (3...
Shih-Yen Ku, Yuh-Jyh Hu
BMCBI
2007
93views more  BMCBI 2007»
13 years 10 months ago
SVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...
BMCBI
2010
123views more  BMCBI 2010»
13 years 5 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
APVIS
2004
13 years 11 months ago
An Interactive Visualisation for Investigating DNA Sequence Information
1 The sequence of nucleotides that makes up a DNA molecule encodes the characteristics of living things. Bioinformatics offers sophisticated methods to search for and compare nucl...
Paul Rutherford, Clare Churcher, John McCallum
CSB
2005
IEEE
223views Bioinformatics» more  CSB 2005»
14 years 3 months ago
Automatic Protein Function Annotation through Candidate Ortholog Clusters from Incomplete Genomes
Annotation of protein function often arises in the context of partially complete genomes but is not adequately addressed. We present an annotation method by extracting ortholog cl...
Akshay Vashist, Casimir A. Kulikowski, Ilya B. Muc...