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» On Computing Complex Navigation Functions
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131
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RECOMB
2005
Springer
16 years 2 months ago
Predicting Protein-Peptide Binding Affinity by Learning Peptide-Peptide Distance Functions
Many important cellular response mechanisms are activated when a peptide binds to an appropriate receptor. In the immune system, the recognition of pathogen peptides begins when th...
Chen Yanover, Tomer Hertz
123
Voted
BMCBI
2007
131views more  BMCBI 2007»
15 years 2 months ago
An improved method for identifying functionally linked proteins using phylogenetic profiles
Background: Phylogenetic profiles record the occurrence of homologs of genes across fully sequenced organisms. Proteins with similar profiles are typically components of protein c...
Shawn Cokus, Sayaka Mizutani, Matteo Pellegrini
FOCS
2007
IEEE
15 years 8 months ago
Parameterized Proof Complexity
We propose a proof-theoretic approach for gaining evidence that certain parameterized problems are not fixedparameter tractable. We consider proofs that witness that a given prop...
Stefan S. Dantchev, Barnaby Martin, Stefan Szeider
123
Voted
BMCBI
2004
196views more  BMCBI 2004»
15 years 2 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
116
Voted
TEC
2010
173views more  TEC 2010»
14 years 9 months ago
Analysis of Computational Time of Simple Estimation of Distribution Algorithms
Estimation of distribution algorithms (EDAs) are widely used in stochastic optimization. Impressive experimental results have been reported in the literature. However, little work ...
Tianshi Chen, Ke Tang, Guoliang Chen, Xin Yao