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BMCBI
2007
13 years 8 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
BMCBI
2008
13 years 8 months ago
2008
Background: Microarray experiments measure changes in the expression of thousands of genes. The resulting lists of genes with changes in expression are then searched for biologica...
BMCBI
2007
13 years 8 months ago
2007
Background: We present a probabilistic topic-based model for content similarity called pmra that underlies the related article search feature in PubMed. Whether or not a document ...
BMCBI
2008
13 years 8 months ago
2008
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
BMCBI
2008
13 years 8 months ago
2008
Background: FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows...