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» On Fitting Mixture Models
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BMCBI
2007
122views more  BMCBI 2007»
13 years 7 months ago
TAP score: torsion angle propensity normalization applied to local protein structure evaluation
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
Silvio C. E. Tosatto, Roberto Battistutta
BMCBI
2008
149views more  BMCBI 2008»
13 years 7 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
CAD
2005
Springer
13 years 7 months ago
Parameterization and parametric design of mannequins
This paper presents a novel feature based parameterization approach of human bodies from the unorganized cloud points and the parametric design method for generating new models ba...
Charlie C. L. Wang
CORR
2002
Springer
96views Education» more  CORR 2002»
13 years 7 months ago
The Sketch of a Polymorphic Symphony
In previous work, we have introduced functional strategies, that is, first-class generic functions that can traverse into terms of any type while mixing uniform and type-specific ...
Ralf Lämmel