Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Background: Existing biological databases support a variety of queries such as keyword or definition search. However, they do not provide any measure of relevance for the instance...
Sequence alignment is an important problem in computational biology. We compare two different approaches to the problem of optimally aligning two or more character strings: bounde...
For an increasing number of modern database applications, efficient support of similarity search becomes an important task. Along with the complexity of the objects such as images...