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BMCBI
2007
13 years 7 months ago
2007
Background: The study of the functional role of alternative splice isoforms of a gene is a very active area of research in biology. The difficulty of the experimental approach (in...
BMCBI
2007
13 years 7 months ago
2007
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
BMCBI
2010
13 years 7 months ago
2010
Background: Extensive and automated data integration in bioinformatics facilitates the construction of large, complex biological networks. However, the challenge lies in the inter...
BMCBI
2010
13 years 7 months ago
2010
Background: Network co-regulated modules are believed to have the functionality of packaging multiple biological entities, and can thus be assumed to coordinate many biological fu...
BMCBI
2008
13 years 7 months ago
2008
Background: In the present investigation, we have used an exhaustive metabolite profiling approach to search for biomarkers in recombinant Aspergillus nidulans (mutants that produ...