Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
Ping Ye, Brian D. Peyser, Forrest A. Spencer, Joel...
It is known that the springlike properties of muscles provide automatic load compensation during weight bearing. How crucial is sensory control of the motor output given these basi...
Background: Subcellular localization of a new protein sequence is very important and fruitful for understanding its function. As the number of new genomes has dramatically increas...
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...