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GECCO
2008
Springer
122views Optimization» more  GECCO 2008»
13 years 11 months ago
Evolving machine microprograms
The realization of a control unit can be done using a complex circuitry or microprogramming. The latter may be considered as an alternative method of implementation of machine ins...
Pedro A. Castillo Valdivieso, G. Fernández,...
BIOINFORMATICS
2010
116views more  BIOINFORMATICS 2010»
13 years 10 months ago
A principal skeleton algorithm for standardizing confocal images of fruit fly nervous systems
Motivation: The fruit fly (Drosophila melanogaster) is a commonly used model organism in biology. We are currently building a 3D digital atlas of the fruit fly larval nervous syst...
Lei Qu, Hanchuan Peng
BMCBI
2010
148views more  BMCBI 2010»
13 years 10 months ago
Applying unmixing to gene expression data for tumor phylogeny inference
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
Russell Schwartz, Stanley Shackney
BMCBI
2010
84views more  BMCBI 2010»
13 years 10 months ago
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis
Background: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to expl...
Benjamin A. Logsdon, Gabriel E. Hoffman, Jason G. ...
BMCBI
2007
135views more  BMCBI 2007»
13 years 10 months ago
Detecting multivariate differentially expressed genes
Background: Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariat...
Roland Nilsson, José M. Peña, Johan ...