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» On Probabilistic Alternating Simulations
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BMCBI
2006
93views more  BMCBI 2006»
13 years 10 months ago
Evaluation of absolute quantitation by nonlinear regression in probe-based real-time PCR
Background: In real-time PCR data analysis, the cycle threshold (CT) method is currently the gold standard. This method is based on an assumption of equal PCR efficiency in all re...
Rasmus Goll, Trine Olsen, Guanglin Cui, Jon Florho...
BMCBI
2006
143views more  BMCBI 2006»
13 years 10 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
BMCBI
2006
116views more  BMCBI 2006»
13 years 10 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2007
147views more  BMCBI 2007»
13 years 10 months ago
Bias in random forest variable importance measures: Illustrations, sources and a solution
Variable importance measures for random forests have been receiving increased attention as a means of variable selection in many classification tasks in bioinformatics and relate...
Carolin Strobl, Anne-Laure Boulesteix, Achim Zeile...
JACIII
2008
148views more  JACIII 2008»
13 years 10 months ago
Optimal Route Based on Dynamic Programming for Road Networks
Abstract. One of the main functions of the traffic navigation systems is to find the optimal route to the destination. In this paper, we propose an iterative Q value updating algor...
Manoj Kanta Mainali, Kaoru Shimada, Shingo Mabu, K...