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» On Relationships Between Query Models
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BMCBI
2008
132views more  BMCBI 2008»
13 years 10 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
BMCBI
2007
112views more  BMCBI 2007»
13 years 10 months ago
PFAAT version 2.0: A tool for editing, annotating, and analyzing multiple sequence alignments
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
Daniel R. Caffrey, Paul H. Dana, Vidhya Mathur, Ma...
BMCBI
2007
153views more  BMCBI 2007»
13 years 10 months ago
Estimating genealogies from linked marker data: a Bayesian approach
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
Dario Gasbarra, Matti Pirinen, Mikko J. Sillanp&au...
DSS
2008
103views more  DSS 2008»
13 years 10 months ago
Explaining clinical decisions by extracting regularity patterns
When solving clinical decision-making problems with modern graphical decision-theoretic models such as influence diagrams, we obtain decision tables with optimal decision alternat...
Concha Bielza, Juan A. Fernández del Pozo, ...
BMCBI
2006
85views more  BMCBI 2006»
13 years 10 months ago
Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shoc
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...
Ester Vilaprinyó, Rui Alves, Albert Sorriba...