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» On Timed Models of Gene Networks
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KDD
2009
ACM
230views Data Mining» more  KDD 2009»
14 years 14 days ago
Grouped graphical Granger modeling methods for temporal causal modeling
We develop and evaluate an approach to causal modeling based on time series data, collectively referred to as“grouped graphical Granger modeling methods.” Graphical Granger mo...
Aurelie C. Lozano, Naoki Abe, Yan Liu, Saharon Ros...
CEC
2008
IEEE
13 years 8 months ago
Regulation of gene regulation - smooth binding with dynamic affinity affects evolvability
Abstract-- Understanding the evolvability of simple differentiating multicellular systems is a fundamental problem in the biology of genetic regulatory networks and in computationa...
Johannes F. Knabe, Chrystopher L. Nehaniv, Maria J...
BMCBI
2006
126views more  BMCBI 2006»
13 years 8 months ago
A joint model of regulatory and metabolic networks
Background: Gene regulation and metabolic reactions are two primary activities of life. Although many works have been dedicated to study each system, the coupling between them is ...
Chen-Hsiang Yeang, Martin Vingron
BMCBI
2005
116views more  BMCBI 2005»
13 years 7 months ago
Dynamic covariation between gene expression and proteome characteristics
Background: Cells react to changing intra- and extracellular signals by dynamically modulating complex biochemical networks. Cellular responses to extracellular signals lead to ch...
Mansour Taghavi Azar Sharabiani, Markku Siermala, ...
BIOINFORMATICS
2005
152views more  BIOINFORMATICS 2005»
13 years 7 months ago
Intervention in context-sensitive probabilistic Boolean networks
Motivation: Intervention in a gene regulatory network is used to help it avoid undesirable states, such as those associated with a disease. Several types of intervention have been...
Ranadip Pal, Aniruddha Datta, Michael L. Bittner, ...