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» On Timed Models of Gene Networks
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BMCBI
2004
207views more  BMCBI 2004»
13 years 7 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...
ICS
2005
Tsinghua U.
14 years 1 months ago
Optimization of MPI collective communication on BlueGene/L systems
BlueGene/L is currently the world’s fastest supercomputer. It consists of a large number of low power dual-processor compute nodes interconnected by high speed torus and collect...
George Almási, Philip Heidelberger, Charles...
BMCBI
2006
142views more  BMCBI 2006»
13 years 8 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins
BMCBI
2007
116views more  BMCBI 2007»
13 years 8 months ago
MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes
Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures pre...
Huaiqiu Zhu, Gang-Qing Hu, Yi-Fan Yang, Jin Wang, ...
BMCBI
2010
109views more  BMCBI 2010»
13 years 8 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...