Codon optimization enhances the efficiency of DNA expression vectors used in DNA vaccination and gene therapy by increasing protein expression. Additionally, certain nucleotide mo...
Ravi Vijaya Satya, Amar Mukherjee, Udaykumar Ranga
Background: Identifying approximately repeated patterns, or motifs, in DNA sequences from a set of co-regulated genes is an important step towards deciphering the complex gene reg...
Given an undirected graph with nonnegative costs on the edges, the routing cost of any of its spanning trees is the sum over all pairs of vertices of the cost of the path between t...
Bang Ye Wu, Giuseppe Lancia, Vineet Bafna, Kun-Mao...
Abstract. We consider the problem of finding shortest paths in a graph with independent randomly distributed edge lengths. Our goal is to maximize the probability that the path len...
Evdokia Nikolova, Jonathan A. Kelner, Matthew Bran...
This paper is concerned with developing an information-theoretic framework to aggregate the state space of a Hidden Markov Model (HMM) on discrete state and observation spaces. The...