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BMCBI
2010
13 years 8 months ago
2010
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
BMCBI
2008
13 years 8 months ago
2008
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
BMCBI
2008
13 years 8 months ago
2008
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
BMCBI
2007
13 years 8 months ago
2007
Background: We investigate the empirical complexity of the RNA secondary structure design problem, that is, the scaling of the typical difficulty of the design task for various cl...
BMCBI
2008
13 years 8 months ago
2008
Background: An important aspect of proteomic mass spectrometry involves quantifying and interpreting the isotope distributions arising from mixtures of macromolecules with differe...