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» On predicting secondary structure transition
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BMCBI
2006
142views more  BMCBI 2006»
13 years 7 months ago
RDMAS: a web server for RNA deleterious mutation analysis
Background: The diverse functions of ncRNAs critically depend on their structures. Mutations in ncRNAs disrupting the structures of functional sites are expected to be deleterious...
Wenjie Shu, Xiaochen Bo, Rujia Liu, Dongsheng Zhao...
JUCS
2010
104views more  JUCS 2010»
13 years 6 months ago
Investigating a Correlation between Subcellular Localization and Fold of Proteins
: When considering the prediction of a structural class for a protein as a classification problem, usually a classifier is based on a feature vector x ∈ Rn , where the features...
Johannes Aßfalg, Jing Gong, Hans-Peter Krieg...
BMCBI
2007
147views more  BMCBI 2007»
13 years 7 months ago
Improved residue contact prediction using support vector machines and a large feature set
Background: Predicting protein residue-residue contacts is an important 2D prediction task. It is useful for ab initio structure prediction and understanding protein folding. In s...
Jianlin Cheng, Pierre Baldi
BMCBI
2008
140views more  BMCBI 2008»
13 years 7 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
CSB
2004
IEEE
115views Bioinformatics» more  CSB 2004»
13 years 11 months ago
PoPS: A Computational Tool for Modeling and Predicting Protease Specificity
Proteases play a fundamental role in the control of intra- and extracellular processes by binding and cleaving specific amino acid sequences. Identifying these targets is extremel...
Sarah E. Boyd, Maria J. García de la Banda,...