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» On properties of cell matrices
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BMCBI
2010
82views more  BMCBI 2010»
13 years 8 months ago
Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation data
Background: DNA replication is a fundamental biological process during S phase of cell division. It is initiated from several hundreds of origins along whole chromosome with diffe...
Huaien Luo, Juntao Li, Majid Eshaghi, Jianhua Liu,...
BMCBI
2006
145views more  BMCBI 2006»
13 years 8 months ago
GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
Kazuharu Arakawa, Yohei Yamada, Kosaku Shinoda, Yo...
BMCBI
2006
124views more  BMCBI 2006»
13 years 8 months ago
Network-based de-noising improves prediction from microarray data
Background: Prediction of human cell response to anti-cancer drugs (compounds) from microarray data is a challenging problem, due to the noise properties of microarrays as well as...
Tsuyoshi Kato, Yukio Murata, Koh Miura, Kiyoshi As...
BMCBI
2005
141views more  BMCBI 2005»
13 years 8 months ago
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...
TRS
2008
13 years 8 months ago
The Neurophysiological Bases of Cognitive Computation Using Rough Set Theory
A popular view is that the brain works in a similar way to a digital computer or a Universal Turing Machine by processing symbols. Psychophysical experiments and our amazing capabi...
Andrzej W. Przybyszewski