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BMCBI
2008
144views more  BMCBI 2008»
13 years 7 months ago
WGCNA: an R package for weighted correlation network analysis
Background: Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method ...
Peter Langfelder, Steve Horvath
BMCBI
2008
147views more  BMCBI 2008»
13 years 7 months ago
Simple integrative preprocessing preserves what is shared in data sources
Background: Bioinformatics data analysis toolbox needs general-purpose, fast and easily interpretable preprocessing tools that perform data integration during exploratory data ana...
Abhishek Tripathi, Arto Klami, Samuel Kaski
BMCBI
2008
132views more  BMCBI 2008»
13 years 7 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
BMCBI
2007
162views more  BMCBI 2007»
13 years 7 months ago
Bioclipse: an open source workbench for chemo- and bioinformatics
Background: There is a need for software applications that provide users with a complete and extensible toolkit for chemo- and bioinformatics accessible from a single workbench. C...
Ola Spjuth, Tobias Helmus, Egon L. Willighagen, St...
BMCBI
2008
87views more  BMCBI 2008»
13 years 7 months ago
Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfa
Background: Empirical binding models have previously been investigated for the energetics of protein complexation (G models) and for the influence of mutations on complexation (i....
Salim Bougouffa, Jim Warwicker