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BMCBI
2007
114views more  BMCBI 2007»
13 years 9 months ago
False occurrences of functional motifs in protein sequences highlight evolutionary constraints
Background: False occurrences of functional motifs in protein sequences can be considered as random events due solely to the sequence composition of a proteome. Here we use a nume...
Allegra Via, Pier Federico Gherardini, Enrico Ferr...
BMCBI
2006
159views more  BMCBI 2006»
13 years 8 months ago
EpiJen: a server for multistep T cell epitope prediction
Background: The main processing pathway for MHC class I ligands involves degradation of proteins by the proteasome, followed by transport of products by the transporter associated...
Irini A. Doytchinova, Pingping Guan, Darren R. Flo...
BMCBI
2007
107views more  BMCBI 2007»
13 years 8 months ago
A computational approach for detecting peptidases and their specific inhibitors at the genome level
Background: Peptidases are proteolytic enzymes responsible for fundamental cellular activities in all organisms. Apparently about 2–5% of the genes encode for peptidases, irresp...
Lisa Bartoli, Remo Calabrese, Piero Fariselli, Dam...
IJCSA
2006
91views more  IJCSA 2006»
13 years 8 months ago
Possibilistic Explanation
The philosophy literature has been struggling with the problem of defining causality. There has been extensive discussion about it. Hume taught that talk of causation was metaphys...
Sara Boutouhami, Aïcha Mokhtari
JCB
2006
115views more  JCB 2006»
13 years 8 months ago
Designing an A* Algorithm for Calculating Edit Distance between Rooted-Unordered Trees
Tree structures are useful for describing and analyzing biological objects and processes. Consequently, there is a need to design metrics and algorithms to compare trees. A natura...
Yair Horesh, Ramit Mehr, Ron Unger