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» On the Complexity of Hardness Amplification
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BMCBI
2010
84views more  BMCBI 2010»
13 years 7 months ago
An integrated analysis of molecular aberrations in NCI-60 cell lines
Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
Chen-Hsiang Yeang
FOCS
2000
IEEE
14 years 2 days ago
On the Hardness of Graph Isomorphism
We show that the graph isomorphism problem is hard under DLOGTIME uniform AC0 many-one reductions for the complexity classes NL, PL (probabilistic logarithmic space) for every loga...
Jacobo Torán
FSTTCS
2010
Springer
13 years 5 months ago
Determining the Winner of a Dodgson Election is Hard
Computing the Dodgson Score of a candidate in an election is a hard computational problem, which has been analyzed using classical and parameterized analysis. In this paper we reso...
Michael R. Fellows, Bart M. P. Jansen, Daniel Loks...
FOCS
2005
IEEE
14 years 1 months ago
Hardness of Approximating the Closest Vector Problem with Pre-Processing
d Abstract] Mikhail Alekhnovich ∗ Subhash A. Khot † Guy Kindler ‡ Nisheeth K. Vishnoi § We show that, unless NP⊆DTIME(2poly log(n) ), the closest vector problem with pre-...
Mikhail Alekhnovich, Subhash Khot, Guy Kindler, Ni...
DAC
1997
ACM
13 years 12 months ago
System-Level Synthesis of Low-Power Hard Real-Time Systems
We present a system-level approach for power optimization under a set of user specified costs and timing constraints of hard real-time designs. The approach optimizes all three d...
Darko Kirovski, Miodrag Potkonjak