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BMCBI
2008
13 years 7 months ago
2008
Background: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increas...
BMCBI
2010
13 years 7 months ago
2010
Background: New technologies are enabling the measurement of many types of genomic and epigenomic information at scales ranging from the atomic to nuclear. Much of this new data i...
BMCBI
2007
13 years 7 months ago
2007
Background: In ribonucleic acid (RNA) molecules whose function depends on their final, folded three-dimensional shape (such as those in ribosomes or spliceosome complexes), the se...
BMCBI
2010
13 years 7 months ago
2010
Background: Pathway-targeted or low-density arrays are used more and more frequently in biomedical research, particularly those arrays that are based on quantitative real-time PCR...
BMCBI
2007
2007
Missing channels in two-colour microarray experiments: Combining single-channel and two-channel data
13 years 7 months ago
Background: There are mechanisms, notably ozone degradation, that can damage a single channel of two-channel microarray experiments. Resulting analyses therefore often choose betw...