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BMCBI
2007
13 years 8 months ago
2007
Background: In recent years, mammalian protein-protein interaction network databases have been developed. The interactions in these databases are either extracted manually from lo...
BMCBI
2010
13 years 8 months ago
2010
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
BMCBI
2010
2010
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
13 years 8 months ago
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
BMCBI
2007
13 years 8 months ago
2007
Background: Metagenomic analyses of microbial communities that are comprehensive enough to provide multiple samples of most loci in the genomes of the dominant organism types will...
BMCBI
2007
13 years 8 months ago
2007
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...