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BMCBI
2007
120views more  BMCBI 2007»
13 years 8 months ago
Re-sampling strategy to improve the estimation of number of null hypotheses in FDR control under strong correlation structures
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
Xin Lu, David L. Perkins
BMCBI
2004
120views more  BMCBI 2004»
13 years 8 months ago
Optimal cDNA microarray design using expressed sequence tags for organisms with limited genomic information
Background: Expression microarrays are increasingly used to characterize environmental responses and hostparasite interactions for many different organisms. Probe selection for cD...
Yian A. Chen, David J. Mckillen, Shuyuan Wu, Matth...
BMCBI
2007
164views more  BMCBI 2007»
13 years 8 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...
CMSB
2006
Springer
14 years 13 days ago
Possibilistic Approach to Biclustering: An Application to Oligonucleotide Microarray Data Analysis
Abstract. The important research objective of identifying genes with similar behavior with respect to different conditions has recently been tackled with biclustering techniques. I...
Maurizio Filippone, Francesco Masulli, Stefano Rov...
HIS
2008
13 years 10 months ago
CBR System for Diagnosis of Patients
Microarray technology allows to measure the expression levels of thousands of genes in an experiment. The use of computational methods is fundamental in cancer research. One of th...
Juan Francisco de Paz, Sara Rodríguez, Javi...