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    BMCBI
    2004
    158views more  BMCBI 2004»
    Incremental genetic K-means algorithm and its application in gene expression data analysis
    13 years 8 months ago
    Incremental genetic K-means algorithm and its application in gene expression data analysis
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    Background: In recent years, clustering algorithms have been effectively applied in molecular biology for gene expression data analysis. With the help of clustering algorithms suc...
    Yi Lu, Shiyong Lu, Farshad Fotouhi, Youping Deng, ...
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    BMCBI
    2010
    106views more  BMCBI 2010»
    TumorBoost: Normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarrays
    13 years 8 months ago
    TumorBoost: Normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarrays
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    Background: High-throughput genotyping microarrays assess both total DNA copy number and allelic composition, which makes them a tool of choice for copy number studies in cancer, ...
    Henrik Bengtsson, Pierre Neuvial, Terence P. Speed
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    BMCBI
    2010
    124views more  BMCBI 2010»
    Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
    13 years 8 months ago
    Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
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    Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
    Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
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    BMCBI
    2007
    101views more  BMCBI 2007»
    Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats
    13 years 8 months ago
    Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats
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    Background: Pyrrolizidine alkaloids (PAs) are probably the most common plant constituents that poison livestock, wildlife, and humans worldwide. Riddelliine is isolated from plant...
    Nan Mei, Lei Guo, Ruqing Liu, James C. Fuscoe, Tao...
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    BMCBI
    2006
    103views more  BMCBI 2006»
    Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
    13 years 8 months ago
    Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
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    Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
    Sébastien Lemieux
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